Personalized Embryo Transfer in Delhi
What is Personalized Embryo Transfer?
Personalized Embryo Transfer in India At Delhi IVF Centre is a test to identify the
window of implantation using ERA test to increase the chances of implantation for
an individual with repeated implantation failure.
What is Window of Implantation?
Personalized embryo transfer during window of implantation is
defined as that period when the uterus is receptive for implantation
of the free-lying blastocyst. The duration of this process of receptivity
is short and thus, results from the arranged sequence of the action of
progesterone and estrogen on the endometrium. Implantation starts with an exchange of
biochemical signals between trophoblast and the endometrium resulting in attachment of
the embryo and decidualization of the uterus. This period is short and for a successful
implantation, it is important to know the exact window of implantation for
embryo transfer for optimum results. Presently, there is no method of knowing
the window of implantation.
Fortunately, Scientist working on this problem has devised a new test for determining the window
of implantation. It is called ERA test.
IVF Treatment Embryo Transfer in Delhi
What is ERA (ERA stands for Endometrial Receptivity Analysis) (or Array) Test?
It is a test to determine the window implantation in cases of recurrent or repeated implantation
failure when everything else seems to be going well. The ERA test is one of the new developments,
which is offering new hope to patients coping with implantation failure. This is a genetic test
in which a small sample of endometrial tissue of a woman is taken to verify whether endometrial
lining is developed to accept an implanting embryo or not? During this receptive period, proteins
are synthesized which make the lining thicker and more suitable for implantation. This usually \
occurs in 84% women at the expected time.
In 16% of women, this window occurs earlier or might be later
than expected. For IVF cycles, it is important to know, that embryo
transfer is being done on the correct or incorrect day, where the
window is unopened or already got closed, which leads to implantation
failure. This test compares the RNA of the receptive period with the
non-receptive period. This test is performed with a small endometrial
biopsy at a very special time of the cycle to find the RNA profile of
the biopsy and compared with the database created during other parts
of the IVF cycle.